simply blood

The 52nd ISEH Annual Scientific Meeting took place at the New York Marriott at the Brooklyn Bridge from 17-20 August 2023. Our Annual Scientific Meeting brought together more than 540 scientists and ISEH members from 25 different countries from around the world. This meeting in New York City was planned for 2020, but it had to be postponed due to the COVID-19 emergency. After three years, we finally got to roll our suitcases down the streets of NYC, which is a fantastic playground for networking. We were extremely happy and grateful to bring the community together again! The Science The meeting included many events that were targeted to a broad audience of scientists at various stages of their careers (from trainees to PIs). We had 31 invited speakers, 26 short talk presenters, 15 featured poster presentations and 217 poster presentations. The scientific sessions covered a wide range of topics from the molecular mechanisms of developmental and adult hematopoiesis, the role of the micro...

As a clinical hematologist, the publication of Living Medicine - a history of the development of bone marrow transplantation in humans - was required reading. However, I was pleasantly surprised to see that Dr. Appelbaum carefully reviews the history of the fundamental basic science of hematopoietic stem cells, the understanding of which forms a required basis for clinical transplantation. From the perspective of an experimental hematologist, it was fascinating to learn how the pioneers of clinical transplantation leveraged fundamental science done in mice into translational studies and iterative clinical trials to progressively develop, improve, and optimize allogeneic bone marrow transplantation. Laboratory based research was vital in the iterative trials that moved bone marrow transplantation from a high-risk intervention for patients with no other options to now a much safer front-line therapy for many blood diseases. Although Dr. Appelbaum justifiably emphasizes the foundatio...

The Laurenti Lab, at Wellcome Cambridge Stem Cell Institute, Cambridge, UK Each month, Simply Blood spotlights a lab contributing to the fields of hematology, immunology, stem cell research, cell and gene therapies, and more. Get to know groups doing cutting edge research from around the world! This month, we are featuring the Laurenti Lab which is based out of the Cambridge Stem Cell Institute, at the University of Cambridge in the UK ( https://www.stemcells.cam.ac.uk/people/pi/laurenti ). How long have you had your lab? And how many members make up your lab? I have started my group in September 2014, and currently our group is composed of seven people. Three postdocs, two PhD students and one research assistant, in addition to several students shared between our group and other research groups including; one bioinformatician and two postdocs. What is the major research theme of your lab? Our lab is interested in deciphering human haematopoiesis across the lifetime, ideally at single...