simply blood

The second edition of the Simply Blood Preprint Watch includes 14 preprints, covering clonal dynamics, AML biology and tumor-immune dynamics! We are also happy to showcase a preprint directly contributed by the community, so if you want to see your preprint featured as well, complete a brief submission form . From the Simply Blood Community : A Pax3 lineage gives rise to transient haematopoietic progenitors https://www.biorxiv.org/content/10.1101/2024.06.26.600366v1  This study describes a new source of transient haematopoietic progenitors in the mouse embryo belonging to a Pax3 lineage. These progenitors appear to be transient EMP-like cells that do not originate in the yolk sac and do not persist in adulthood.  STEM AND PROGENITOR CELLS BIOLOGY Hematopoietic Tet2 inactivation enhances the response to checkpoint blockade immunotherapy https://www.biorxiv.org/content/10.1101/2024.09.09.612140v1 Somatic mutations in TET2, a common driver of clonal hematopoiesis, enhance the res...

This week on Simply Blood we interviewed the 2024 Award Winner for Leadership in Diversity, Equity and Inclusion, Katherine King, MD, PhD . Dr. King shares tips and activities to build an inclusive lab environment, how to be a better mentor and role model of DEI, and highlights her lab's research! 2024 Leadership in Diversity, Equity and Inclusion Award Winner Katherine King, MD, PhD Professor, Pediatrics-Infectious Disease Baylor College of Medicine Houston, TX Learn more about Dr. King's contributions to DEI by reading her latest blog post published in Baylor College of Medicine, Easy ways to incorporate inclusion into a busy academic life . Interviewed by Alba Rodriguez-Meira of the ISEH New Investigators Committee. Please note that the statements made by Simply Blood Authors are their own views and not necessarily the views of ISEH. ISEH disclaims any or all liability arising from any author's statements or materials.

  Each month, Simply Blood spotlights a lab contributing to the fields of hematology, immunology, stem cell research, cell and gene therapies, and more. Get to know groups doing cutting edge research from around the world! This month, we are featuring the Vanuytsel Lab which is based out of the Center for Regenerative Medicine, Boston University. How long has your lab been open and who is in your lab currently? The lab opened in July 2023 and currently consists of a lab manager, a PhD student, a postdoc and three undergraduate researchers. What is the overarching research goal for your group? Our lab studies concepts at the intersection of hematopoietic development, stem cell biology and sickle cell disease. We are trying to gain an in-depth understanding of engraftment potential and how that is orchestrated during development so that we can harness those insights to improve stem cell engraftment in the context of gene therapy and stem cell transplantations. What we learn from stu...