Preprint Deep Dive on AML Biology

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Publications Committee Member Alessandro Donada (Institute Curie, Paris, France) recently sat down to interview Dorien Pastoors (Erasmus MC, Rotterdam, Netherlands) and Travis Fleming (Broad Institute, Boston, USA) and discuss their recent preprints on AML Biology. Watch the brief interview and check out their preprints below. 



MECOM is a master repressor of myeloid differentiation through dose control of CEBPA in acute myeloid leukemia

Dorien Pastoors, Marije Havermans, Roger Mulet-Lazaro, Leonie Smeenk, Sophie Ottema, Claudia Erpelinck-Verschueren, Stanley van Herk, Maikel Anthonissen, Tim Grob, Bas J. Wouters, Berna Beverloo, Torsten Haferlach, Claudia Haferlach, Johannes Zuber, Eric Bindels, Ruud Delwel

CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias

Travis J. Fleming, Mateusz Antoszewski, Sander Lambo, Michael C. Gundry, Riccardo Piussi, Lara Wahlster, Sanjana Shah, Fiona E. Reed, Kevin D. Dong, Joao A. Paulo, Steven P. Gygi, Claudia Mimoso, Seth R. Goldman, Karen Adelman, Jennifer A. Perry, Yana Pikman, Kimberly Stegmaier, Maria N. Barrachina, Kellie R. Machlus, Volker Hovestadt, Andrea Arruda, Mark D. Minden, Richard A. Voit, Vijay G. Sankaran


Have a preprint you'd like featured by ISEH? Submit a preprint on our website.


Blog post contributed by Alessandro Donada, PhD (Bluesky: @alessandrodonada.bsky.social) of the ISEH Publications Committee. 

Please note that the statements made by Simply Blood authors are their own views and not necessarily the views of ISEH. ISEH disclaims any or all liability arising from any author's statements or materials.


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