simply blood

Welcome to our monthly Preprint Watch, where we highlight some of the most relevant preprints for the ISEH community! This month we cover some exciting findings on immunotherapy, hematopoietic fetal development and erythropoiesis. If you would like to see your preprint highlighted here, complete this brief form . We are also happy to chat with Dr. Jane Xu, she will tell us more about chromatin accessibility and leukemia development!  From the Simply Blood Community: Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia https://www.biorxiv.org/content/10.1101/2025.03.19.643917v1 From the authors: We developed humanized models to investigate how the developmental origin of hematopoietic stem and progenitor cells influences leukemia initiation, lineage plasticity, and therapeutic response in pediatric leukemias driven by NUP98 fusion oncoproteins. Our study reveals fundamental developmental differences underlying lineage potential and dru...

Espin Lab Each month, Simply Blood spotlights a lab contributing to the fields of hematology, immunology, stem cell research, cell and gene therapies, and more. Get to know groups doing cutting edge research from around the world! This month, we are featuring the  Espin Lab   which is based out of Iowa State University. How long have you had your lab? I started my lab in August 2019, so 5.5 years. How many members make up your lab? In the last year, the lab has reduced its size due to four graduations, one retirement, and one postdoc who transitioned to a faculty position, so we are in the process of hiring. Currently, in my lab there are two PhD students, a lab manager, and four undergraduate researchers. However, our lab operates together with the lab of Dr. Clyde Campbell, husband and Assistant Professor at ISU, which adds two more PhD students to the group. Both of our labs work as a team, sharing research resources and mentorship. It is therefore hard to separate the memb...

  This week on Simply Blood, we interviewed last year's Award Winner for Leadership in Mentorship, Ross Levine, MD . Dr. Levine shares lessons learned, advice for those who are beginning with their first hires, and words of wisdom for helping mentees set long-term goals. Learn more about the Levine Lab . Ross Levine, MD Senior Vice President Memorial Hospital Translational Research Blog post contributed by members of the ISEH Junior Investigator Committee. Please note that the statements made by Simply Blood authors are their own views and not necessarily the views of ISEH. ISEH disclaims any or all liability arising from any author's statements or materials.